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Caro-Kann

There are approx. a dozen setups both for White and for Black.

Precise question, precise answer.
The main plan is to exploit the spatial advantage in the endgame. Example:

Another plan is associated with an attack on the position of the black king.

For blacks instead of move 17. ... cd, it is interesting to try the move17. ... c4!? With the idea, if White makes a sacrifice, open the file "c".
With c7-c5, Black is late, but without this move, choosing protection by exchanging pieces and moving on to the endgame, Black gets a hopeless endgame.
In summary: Protection Karo-Kan has no prospects in the game at the highest level.
@ujcn you sure? Weird that all of the following players played this opening "without prospects at highest levels" during last 5 years: Mamedyarov, Caruana, Anand, Nakamura, Giri, So, Ding, Grischuk, Karjakin, Navara, Topalov, Bacrot and quite some others.

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