@VTWood "The striking part of his statement is the utter ignorance he displays as to Regan's work."
Meh, I found Caruana's thoughts and explanations well-thought out. His assessments clear, fair and aware of possible pitfalls. Caruana's claim comes down to type II error, or in diagnostics the problems of sensitivity (true positives) and specificity (true negatives). There is nothing wrong with his idea that Regan's analysis, like all such analyses, is imperfect and may lead to false positives and false negatives. Nothing to do with 'utter ignorance'.
Especially given the negative consequences of false positives in professional chess, the specificity is somewhat more emphasized. This has the downside that the rate of false negatives is necessarily somewhat higher than in most online cheating detection. It is, as I am used to seeing from Caruana, a clear, lucid and logical position.